Tuesday, July 16, 2013

Kenya raises price of petrol, diesel at the pump

NAIROBI (Reuters) - Kenya's energy regulator raised retail fuel prices for petrol and diesel on Sunday due to rising global oil prices and a weaker local currency, while decreasing the price of kerosene.

Fuel prices have a big impact on the rate of inflation in the east African economy. The rate rose to 4.91 percent in June from 4.05 percent a month earlier.

The economy heavily depends on diesel for transport, power generation and agriculture. Kerosene is used in many households for lighting and cooking.

The Energy Regulatory Commission (ERC) reviews domestic energy prices every month, with adjustments made depending on fluctuations in international energy prices and foreign exchange fluctuations.

The cost of importing super petrol and diesel in June rose, while that of kerosene fell, while at the same time the Kenyan shilling weakened to 85.65 per dollar from 84.30 per dollar in the previous month the ERC said in a statement.

The regulator raised the maximum price of a litre of super petrol in Nairobi by 1.34 shillings to 109.52 shillings, and increased the price of diesel by 3.70 shillings to 102.86 shillings per litre.

The price of kerosene will fall by 2.03 shillings to 79.49 shillings, the commission said.

The new prices will take effect on July 15, and will be in force for a month.

Source: http://news.yahoo.com/kenya-raises-price-petrol-diesel-pump-051014587.html

Kimberly McCarthy Ausar Walcott SB5 NBA Draft 2013 Jrue Holiday Jillian Bynes jodie sweetin

Monday, July 15, 2013

Yahoo accepting requests for inactive email IDs

SAN FRANCISCO (AP) ? Yahoo is allowing people to place claims on inactive email addresses that are being given a second life.

The opportunity to request the identifications began Monday afternoon and will extend through August 7. Up to five different names can be submitted at http://wishlist.yahoo.com .

Yahoo Inc. says a substantial number of old email IDs are being made available, but isn't providing specifics.

The email IDs are being released a month after the Sunnyvale, Calif., company notified users that they would have 30 days to log into an inactive account if they wanted to keep it.

People awarded the rights to the recycled email addresses will have a 48-hour period to activate the accounts beginning Aug. 15.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-07-15-Yahoo%20IDs/id-0bd764a84edd4b3ba5549ba8af62b611

Kohls Black Friday www.walmart.com Macho Camacho Rise of the Guardians Pumpkin Pie Jack Taylor Apple Pie Recipe

Carnegie Mellon researchers develop artificial cells to study molecular crowding and gene expression

Carnegie Mellon researchers develop artificial cells to study molecular crowding and gene expression [ Back to EurekAlert! ] Public release date: 14-Jul-2013
[ | E-mail | Share Share ]

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University

Tightly packed macromolecules enhance gene expression in artificial cellular system

PITTSBURGHThe interior of a living cell is a crowded place, with proteins and other macromolecules packed tightly together. A team of scientists at Carnegie Mellon University has approximated this molecular crowding in an artificial cellular system and found that tight quarters help the process of gene expression, especially when other conditions are less than ideal.

As the researchers report in an advance online publication by the journal Nature Nanotechnology, these findings may help explain how cells have adapted to the phenomenon of molecular crowding, which has been preserved through evolution. And this understanding may guide synthetic biologists as they develop artificial cells that might someday be used for drug delivery, biofuel production and biosensors.

"These are baby steps we're taking in learning how to make artificial cells," said Cheemeng Tan, a Lane Postdoctoral Fellow and a Branco-Weiss Fellow in the Lane Center for Computational Biology, who led the study. Most studies of synthetic biological systems today employ solution-based chemistry, which does not involve molecular crowding. The findings of the CMU study and the lessons of evolution suggest that bioengineers will need to build crowding into artificial cells if synthetic genetic circuits are to function as they would in real cells.

The research team, which included Russell Schwartz, professor of biological sciences; Philip LeDuc, professor of mechanical engineering and biological sciences; Marcel Bruchez, professor of chemistry; and Saumya Saurabh, a Ph.D. student in chemistry, developed their artificial cellular system using molecular components from bacteriophage T7, a virus that infects bacteria that is often used as a model in synthetic biology.

To mimic the crowded intracellular environment, the researchers used various amounts of inert polymers to gauge the effects of different density levels.

Crowding in a cell isn't so different from a crowd of people, Tan said. If only a few people are in a room, it's easy for people to mingle, or even to become isolated. But in a crowded room where it's hard to move around, individuals will often tend to stay close to each other for extended periods. The same thing happens in a cell. If the intracellular space is crowded, binding between molecules increases.

Notably, the researchers found that the dense environments also made gene transcription less sensitive to environmental changes. When the researchers altered concentrations of magnesium, ammonium and spermidine chemicals that modulate the stability and binding of macromolecules they found higher perturbations of gene expression in low density environments than in high density environments.

"Artificial cellular systems have tremendous potential for applications in drug delivery, bioremediation and cellular computing," Tan said. "Our findings underscore how scientists could harness functioning mechanisms of natural cells to their advantage to control these synthetic cellular systems, as well as in hybrid systems that combine synthetic materials and natural cells."

###

This work was supported by grants from the National Institutes of Health and the National Science Foundation, as well as Tan's Lane Postdoctoral Fellowship and his Society in Science Branco Weiss Fellowship. The Lane Center for Computational Biology is part of Carnegie Mellon's School of Computer Science.

About Carnegie Mellon University: Carnegie Mellon (http://www.cmu.edu) is a private, internationally ranked research university with programs in areas ranging from science, technology and business, to public policy, the humanities and the arts. More than 12,000 students in the university's seven schools and colleges benefit from a small student-to-faculty ratio and an education characterized by its focus on creating and implementing solutions for real problems, interdisciplinary collaboration and innovation. A global university, Carnegie Mellon has campuses in Pittsburgh, Pa., California's Silicon Valley and Qatar, and programs in Africa, Asia, Australia, Europe and Mexico. The university recently completed "Inspire Innovation: The Campaign for Carnegie Mellon University," exceeding its $1 billion goal to build its endowment, support faculty, students and innovative research, and enhance the physical campus with equipment and facility improvements. The campaign closed June 30, 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Carnegie Mellon researchers develop artificial cells to study molecular crowding and gene expression [ Back to EurekAlert! ] Public release date: 14-Jul-2013
[ | E-mail | Share Share ]

Contact: Byron Spice
bspice@cs.cmu.edu
412-268-9068
Carnegie Mellon University

Tightly packed macromolecules enhance gene expression in artificial cellular system

PITTSBURGHThe interior of a living cell is a crowded place, with proteins and other macromolecules packed tightly together. A team of scientists at Carnegie Mellon University has approximated this molecular crowding in an artificial cellular system and found that tight quarters help the process of gene expression, especially when other conditions are less than ideal.

As the researchers report in an advance online publication by the journal Nature Nanotechnology, these findings may help explain how cells have adapted to the phenomenon of molecular crowding, which has been preserved through evolution. And this understanding may guide synthetic biologists as they develop artificial cells that might someday be used for drug delivery, biofuel production and biosensors.

"These are baby steps we're taking in learning how to make artificial cells," said Cheemeng Tan, a Lane Postdoctoral Fellow and a Branco-Weiss Fellow in the Lane Center for Computational Biology, who led the study. Most studies of synthetic biological systems today employ solution-based chemistry, which does not involve molecular crowding. The findings of the CMU study and the lessons of evolution suggest that bioengineers will need to build crowding into artificial cells if synthetic genetic circuits are to function as they would in real cells.

The research team, which included Russell Schwartz, professor of biological sciences; Philip LeDuc, professor of mechanical engineering and biological sciences; Marcel Bruchez, professor of chemistry; and Saumya Saurabh, a Ph.D. student in chemistry, developed their artificial cellular system using molecular components from bacteriophage T7, a virus that infects bacteria that is often used as a model in synthetic biology.

To mimic the crowded intracellular environment, the researchers used various amounts of inert polymers to gauge the effects of different density levels.

Crowding in a cell isn't so different from a crowd of people, Tan said. If only a few people are in a room, it's easy for people to mingle, or even to become isolated. But in a crowded room where it's hard to move around, individuals will often tend to stay close to each other for extended periods. The same thing happens in a cell. If the intracellular space is crowded, binding between molecules increases.

Notably, the researchers found that the dense environments also made gene transcription less sensitive to environmental changes. When the researchers altered concentrations of magnesium, ammonium and spermidine chemicals that modulate the stability and binding of macromolecules they found higher perturbations of gene expression in low density environments than in high density environments.

"Artificial cellular systems have tremendous potential for applications in drug delivery, bioremediation and cellular computing," Tan said. "Our findings underscore how scientists could harness functioning mechanisms of natural cells to their advantage to control these synthetic cellular systems, as well as in hybrid systems that combine synthetic materials and natural cells."

###

This work was supported by grants from the National Institutes of Health and the National Science Foundation, as well as Tan's Lane Postdoctoral Fellowship and his Society in Science Branco Weiss Fellowship. The Lane Center for Computational Biology is part of Carnegie Mellon's School of Computer Science.

About Carnegie Mellon University: Carnegie Mellon (http://www.cmu.edu) is a private, internationally ranked research university with programs in areas ranging from science, technology and business, to public policy, the humanities and the arts. More than 12,000 students in the university's seven schools and colleges benefit from a small student-to-faculty ratio and an education characterized by its focus on creating and implementing solutions for real problems, interdisciplinary collaboration and innovation. A global university, Carnegie Mellon has campuses in Pittsburgh, Pa., California's Silicon Valley and Qatar, and programs in Africa, Asia, Australia, Europe and Mexico. The university recently completed "Inspire Innovation: The Campaign for Carnegie Mellon University," exceeding its $1 billion goal to build its endowment, support faculty, students and innovative research, and enhance the physical campus with equipment and facility improvements. The campaign closed June 30, 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-07/cmu-cmr071213.php

cj wilson ellsbury brad pitt and angelina jolie brad and angelina herniated disc luke scott tom benson

Sunday, July 7, 2013

Rolling Stones deliver biggest bang in nostalgic London show

By Paul Casciato

LONDON (Reuters) - The Rolling Stones blasted through the past into the present on Saturday with a rip-roaring show in London's Hyde Park that paid homage to their last concert here 44 years ago.

Frontman Mick Jagger strutted, howled and belted his way through a two-hour set that gave a nod to founding member Brian Jones, whose death in 1969 turned their last appearance at the royal park into a tribute.

"Anybody out there who was here in 1969?" Jagger called out to applause from a sea of grey hair after opening with "Start Me Up" and "It?s only Rock and Roll".

"Well welcome back, it's nice to see you again."

Jones had already left the Stones the last time Jagger, guitarist Keith Richards and drummer Charlie Watts played the park at a gig meant to introduce his replacement, Mick Taylor. Guitarist Ronnie Wood joined in 1975.

But two days before their appearance, the 27-year-old Jones drowned in his swimming pool under the influence of drugs and alcohol, turning that concert into a commemoration.

Now the band with an average age of 69 stormed through the classics from "Brown Sugar" and "Honky Tonk Woman" to "Jumpin' Jack Flash" and "Sympathy for the Devil" - with rubber-lipped Jagger strumming the guitar for the latest single "Doom and Gloom".

The Stones bounded across the stage and along a catwalk stretching into the sea of 65,000 fans gathered on a sultry summer evening in 21st century central London, sipping beer. The unmistakable aroma of marijuana wafted in the air.

The night belonged to the reconciliation of past and present for a crowd of old and young steeped in Stones lore, watching the band on stage with images of past concerts occasionally flashing past on big screens rising up behind the band.

Jagger donned a white smock-like outfit similar to the one he wore in 1969, played the harmonica and quoted a piece of poetry. The references to Jones and the old days were unmistakable even if his name was never mentioned.

MICK TAYLOR TAKES A BRIEF TURN

Taylor - who left the Stones in 1974 - appeared on stage for a rollicking version of "Midnight Rambler," where he delivered a masterclass in the guitar solo before jamming in front of Watts with Wood and Richards.

"Mick's very first show was with us here," Jagger told the crowd. "We found him in a pub and put him in front of 250,000 people."

The crowd reflected the longevity of the band and their continued popularity across the generations.

"This is my birthday present from my dad," said 34-year-old Dan Kemsley, who had been waiting in front of the stage alongside his Stones-mad father John since noon.

Nostalgia has played a major part in the Rolling Stones' activities the past year as they celebrated 50 years in the music business and embarked on a North American tour.

The Rolling Stones lived up to their reputation as one of the greatest rock and roll bands when they played to more than 100,000 revelers at last weekend's Glastonbury festival.

The band emerged alongside the Beatles in the early 1960s to become one of the most successful groups in rock and roll history with hits such as "You Can't Always Get What You Want" and "Satisfaction", which rounded off the show amid fireworks.

They last went on the road for their "A Bigger Bang" tour from 2005 to 2007, playing 144 shows around the world and grossing more than $550 million, making it one of the world's most lucrative rock tours.

They play another concert in Hyde Park on July 13.

Live performances have emerged as the major money earner in the music business as record sales go digital, with growing numbers of veteran acts returning to the stage and attracting well-heeled, aging fans willing to pay high ticket prices.

(Editing by Philip Barbara)

Source: http://news.yahoo.com/rolling-stones-deliver-biggest-bang-nostalgic-london-show-013645811.html

awkward awkward Girls Love Beyonce gun control Patton Oswalt Outside Lands washington post